Course registration is closed
The course is fully booked. The next instance of this course will be Spring/Summer 2026. Check back on this website in early 2026.


The advanced course in Metabolic Engineering & Systems Biology (MESB) is organized by the Systems and Synthetic Biology division at Chalmers University of Technology, and is intended for PhD students, postdocs, and industrial researchers that are interested in computational aspects of metabolic engineering.

Aim & content

The aim of the course is to provide participants with a strong primer of various (computational) aspects of metabolic engineering. In particular, the course covers the following topics:

  • Constraint-based genome-scale modelling
  • Enzyme-constrained modelling
  • Fermentation technologies
  • Proteomics technologies
  • RNAseq data generation and analysis
  • Integrative gene-expression data analysis

A central question in all the activities is How can I use this in my metabolic engineering project?

Teaching format

The course is intensive and will require precourse studying of material that will be provided closer to the start date. During the course, teaching will be via lectures, while also significant time (most afternoons) is allocated for hands-on computer exercises.


Eduard KerkhovenJosé Luis Martínez RuizPetri-Jaan LahtveeVerena SiewersYun Chen
CHALMERS, SwedenDTU, DenmarkTalTech, EstoniaCHALMERS, SwedenCHALMERS, Sweden